Infectious Disease
mtrR promoter deletion not needed for N. gonorrhoeae drug resistance
Published in TB and Outbreaks Week, February 18th, 2003
S. L. Cousin and coauthors examined the impact of the "macrolide-lincosamide-streptogramin B resistance genes erm(B), erm(C) and erm(F), the macrolide resistance mef(A) gene, and the DNA sequence of a 13 bp repeat in the promoter region of the mtrR gene" Neisseria gonorrhoeae antibiotic susceptibility.
"Eleven isolates with erythromycin and azithromycin MICs of less than or equal to 0.06 mg/L had no acquired genes or deletions in the 13 bp repeat region," Cousin and colleagues found. ...
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