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Infectious Disease

Genomic diversity of enterohemorrhagic E. coli O157 revealed

Published in TB and Outbreaks Week, February 25th, 2003

"Enterohemorrhagic Escherichia coli O157 is one of the leading worldwide public health concerns, causing large outbreaks of hemorrhagic colitis as well as numerous small outbreaks and sporadic cases," according to recent research from Japan.

"The variability of restriction enzyme-digestion patterns of O157 genomes, which is widely used to distinguish strains in the molecular epidemiology of O157 infections, suggests the presence of some genomic diversity among the strains," explained M. Ohnishi and coauthors, Miyazaki Medical College.

"Based on the complete genome sequence of O157 Sakai," Ohnishi and coauthors" analyzed the whole genome...

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