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Infectious Disease Therapy

 Enterobacteriaceae multidrug resistance strongly integron-associated

Published in TB and Outbreaks Week, March 4th, 2003

Researchers in the Netherlands have provided new insight into the development of Enterobacteriaceae drug resistance.

M.A. Leverstein-Van Hall and colleagues at University Medical Center Utrecht "investigated the extent to which multidrug resistance (MDR) among Enterobacteriaceae is related to DNA elements called 'integrons,' whether the relationship is species dependent or origin dependent, and which resistance patterns are associated with integrons."

"Analysis of 867 nonrepeat isolates comprising eight species and originating from the community and 23 European hospitals showed a significant relation between MDR and integrons,...

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