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Infectious Disease Therapy

Terbinafine effective against Aspergillus, Cladosporium fungi

Published in TB and Outbreaks Week, March 11th, 2003

The antifungal agent terbinafine is effective against pathogenic Aspergillus and Cladosporium species.

In a recent study from Turkey, "the in vitro fungicidal and fungistatic activities of terbinafine were compared with those of itraconazole and amphotericin B against Aspergillus (n=63) and Cladosporium (n=21) isolates."

"The broth macrodilution modification of NCCLS reference method for filamentous fungi (M38-P) was used to assess the minimum inhibitory concentrations (MICs)," noted A.S. Kantarcioglu and coauthors, Istanbul University.

The results showed that "the in vitro activities of terbinafine...

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