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Antibiotic Resistance

Overuse cited in Cipro ineffectiveness

Published in TB and Outbreaks Week, March 11th, 2003

Cipro, the antibiotic that became a household word during the 2001 anthrax scare, is becoming increasingly ineffective against other dangerous germs because of overuse, a study found.

The researchers examined data on infections in hospitalized patients in 43 states and Washington, DC, from 1994 to 2000. Ailments included respiratory and urinary infections caused by a variety of bacteria.

Many germs had grown resistant to fluoroquinolones, a class of antibiotics that includes ciprofloxacin, known by the brand name Cipro.

In 1994, Cipro was effective against 86% of the bacteria samples analyzed, but that dropped to 76% by 2000, the...

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