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Infectious Disease Therapy

Ampicillin/sulbactam effective against resistant Acinetobacter

Published in TB and Outbreaks Week, March 25th, 2003

Ampicillin/sulbactam can be safely and effectively used to treat refractory Acinetobacter infections.

In a recent study from Brazil, "forty consecutive patients with nosomial infections caused by multidrug-resistant Acinetobacter baumannii were treated with intravenous ampicillin/sulbactam."

Most of the treated patients suffered from "severe infections with underlying conditions (median APACHE II score: 14.5) and 72.5% occurred in the ICU," according to A. S. Levin and colleagues at the University of Sao Paulo.

After treatment, "twenty-seven (67.5%) were improved/cured, seven (17.5%) were failures and six (15%) were...

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