Published in TB and Outbreaks Week, April 1st, 2003
"Azole antifungals are widely used to treat infections with dermatophyte fungi," researchers in Austria explained. "Whereas it is well established that this class of drugs interferes with fungal ergosterol synthesis, little is known about its potential other biological effects."
A. Uthman and colleagues at the University of Vienna examined the "isolation and structural organization of the Microsporum canis metallothionein gene," and found that "fluconazole is able to downregulate the baseline as well as copper-induced expression of this gene."
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