Infectious Disease

Mannose-binding lectin gene mutations influence hepatitis B outcome

Published in TB and Outbreaks Week, April 1st, 2003

Mutations in the mannose-binding lectin (MBL) gene can influence the outcome of hepatitis B.

According to a study from Germany, MBL "is a constituent of the human innate immune system which may play an important role in combating a variety of infectious diseases."

L. H. Song and colleagues at the University of Tuebingen "investigated the distribution of MBL gene mutations in a Vietnamese population, using polymerase chain reaction and DNA sequence analysis, and sought associations with the outcome of hepatitis B virus (HBV) infection."

Song and coworkers "used samples from a total of 123 patients with confirmed, well-defined HBV...

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Source: TB and Outbreaks Week (2003-04-01)

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