Infectious Disease Therapy

Caspofungin effective against drug-resistant fungal pathogens

Published in TB and Outbreaks Week, April 15th, 2003

Caspofungin is effective against fungal pathogens resistant to conventional treatments.

This agent "is an echinocandin antifungal agent with broad-spectrum activity against Candida and Aspergillus spp.," researchers in the United States explained.

In a study conducted by M. A. Pfaller and coauthors at the University of Iowa, "the in vitro activities of caspofungin against 3,959 isolates of Candida spp. obtained from over 95 different medical centers worldwide were compared with those of fluconazole and itraconazole."

"The MICs of the antifungal drugs were determined by broth microdilution tests performed...

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Source: TB and Outbreaks Week (2003-04-15)

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