Hepatitis C Therapy
Infectious HCV pseudo-particles may help develop new treatments
Published in TB and Outbreaks Week, April 29th, 2003
"The study of hepatitis C virus, a major cause of chronic liver disease, has been hampered by the lack of a cell culture system supporting its replication. ... [W]e have successfully generated infectious pseudo-particles that were assembled by displaying unmodified and functional HCV glycoproteins onto retroviral and lentiviral core particles," reported B. Bartosch and colleagues.
They used a green fluorescent protein marker gene within the pseudo-particles to visualize HCV glycoprotein-mediated...
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