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Tuberculosis Diagnosis

Novel genotype assay effective for drug resistance testing

Published in TB and Outbreaks Week, May 6th, 2003

A novel genotype assay quickly and accurately identifies drug-resistant tuberculosis infections.

"Rapid detection of drug resistance in Mycobacterium tuberculosis is essential for efficient treatment and control of this pathogen," researchers in China noted.

In a study conducted by X.Y. Fan and colleagues at the Shanghai Institute of Biological Products, "the amplification refractory mutation system (ARMS) was used to detect mutations in the rifampin resistance-determining region of the rpoB gene."

"A total of 39 rifampin-resistant M. tuberculosis isolates in Shanghai were analyzed by this assay," they wrote,...

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