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Tuberculosis Diagnosis

Ziehl-Neelsen-stained slides enable resistance testing without culture

Published in TB and Outbreaks Week, May 6th, 2003

Ziehl-Neelsen-stained slides can be used to test for tuberculosis drug resistance without culture.

"Multidrug resistance among new cases of tuberculosis (TB) is increasingly becoming a significant problem in countries with a high prevalence of TB and with inadequate therapies for TB," researchers in the Netherlands explained. "Rifampin resistance is widely used as a marker for multidrug-resistant (MDR) TB; therefore, a new approach to the retrospective measurement of rifampin resistance without the need of a viable culture has been introduced."

"In many developing countries culture is unavailable and diagnosis relies on clinical manifestations and...

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