Published in TB and Outbreaks Week, May 27th, 2003
"The host response to microbial infection is associated with the release of inflammatory mediators. We hypothesized that the type and degree of the systemic response as reflected by levels of circulating mediators predict morbidity and mortality, according to the invasiveness of microbial infection," wrote A.B.J. Groeneveld and colleagues, Free University of Amsterdam, in the journal Clinical Immunology.
To test this, the researchers measured circulating levels of activated complement C3a, interleukin (IL)-6, and...
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