Infectious Disease
Clinical disinfectants trigger pseudomonal drug resistance
Published in TB and Outbreaks Week, June 10th, 2003
According to published research from Japan, "induction of the MexCD-OprJ multidrug efflux pump was investigated in wild-type Pseudomonas aeruginosa PAO1."
"MexCD-OprJ was induced by clinically important disinfectants such as benzalkonium chloride and chlorhexidine gluconate, and by some cytotoxic agents such as tetraphenylphosphonium chloride, ethidium bromide and rhodamine 6G," Y.J. Morita and colleagues reported.
"MexCD-OprJ was not induced by norfloxacin, tetracycline, chloramphenicol, streptomycin, erythromycin or carbenicillin,...
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