Tuberculosis Therapy
Fluoroquinolones, linezolid combine synergistically with standard drugs
Published in TB and Outbreaks Week, June 17th, 2003
In a recent study, scientists in Spain "evaluated the in vitro activity against Mycobacterium tuberculosis of the combination of fluoroquinolones and linezolid with classical drugs."
"The combination of isoniazid with fluoroquinolones had synergic activity in nine of the ten isoniazid-susceptible strains," reported J.C.R. Diaz and coauthors working at Miguel Hernandez University in Alicante.
Test results also revealed "synergism between rifampicin and linezolid in five of the 15 strains susceptible to rifampicin," they...
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