Published in TB and Outbreaks Week, June 24th, 2003
Mycobacterial pantothenate synthetase "catalyzes the formation of pantothenate from ATP, D-pantoate, and beta-alanine," researchers in the United States explained.
In a study from Texas A&M University, "the formation of a kinetically competent pantoyl-adenylate intermediate was established by the observation of a positional isotope exchange (PIX) reaction within O-18-labeled ATP in the presence of D-pantoate."
"When [betagamma-(18)O6]-ATP was incubated with pantothenate synthetase in the presence of D-pantoate, an 18(O)...
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