Infectious Disease Vaccine
DNA immunization effective against MRSA
Published in TB and Outbreaks Week, July 1st, 2003
MRSA is "a major pathogen responsible for serious hospital infections worldwide," explained Jose P.M. Senna and colleagues at the Universidade Federal do Rio Grande do Sul and the Pontificia Universidade Catolica do Rio Grande do Sul. "These bacteria are resistant to all beta-lactam antibiotics due to the production of an additional penicillin binding protein, the PBP2a, encoded by the mecA gene, which shows low affinity for this class of antibiotics."
A vaccine based on the PBP2a protein elicited robust...
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