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Infectious Disease Therapy

Amoxicillin-clavulanic acid still effective

Published in TB and Outbreaks Week, July 8th, 2003

Despite extensive use over 2 decades, amoxicillin-clavulanic acid remains effective against a wide variety of bacterial pathogens.

Scientists in the United States conducted a study to "determine the in vitro activity of amoxicillin-clavulanic acid compared to that of four newer antimicrobial agents (ampicillin, azithromycin, cefuroxime and trimethoprim-sulfamethoxazole)."

"All of the agents were tested against 21,232 recent clinical isolates encompassing 37 species submitted from 16 European countries between 1997 and 1999," noted D.J. Hoban and colleagues at the Laboratories International for Microbiology Studies in Schaumburg, Illinois.

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