Food-Borne Illness

Cross-talk between bacteria, host leads to E. coli infection

Published in TB and Outbreaks Week, July 22nd, 2003

A strain of E. coli that causes severe, sometimes deadly, intestinal problems relies on signals from beneficial human bacteria and a stress hormone to infect human cells, a researcher at the University of Texas Southwestern Medical Center at Dallas has discovered.

The finding, which appeared online June 30, 2003, in Proceedings of the National Academy of Sciences, could lead to the development of beta blockers as a therapy to impede this cellular signaling system, causing the harmful bacteria to pass blindly through the digestive tract, said Dr. Vanessa Sperandio, lead author of the study.

"You're not really attacking the bacteria per...

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Source: TB and Outbreaks Week (2003-07-22)

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