Infectious Disease Therapy
Novel liquid chromatography methods improve erythromycin monitoring
Published in TB and Outbreaks Week, July 29th, 2003
Scientists in Belgium conducted "a comparison of two LC methods for the separation of erythromycin".
"The first method was previously developed in this laboratory and uses an Xterra RP18 column," according to P. Dehouck and colleagues at the Catholic University of Leuven. "Acetonitrile 0.2 M K2HPO4 pH 70 - water (35:5:60) is used as a mobile phase."
"The second method was developed by Abbott and uses an Astec C 18 polymeric column. The mobile phase consists of acetonitrile - 0.2 M K2HPO4 pH 9.0 - water (40:6:54)," the report indicated....
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