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Bacteriology

Enterotoxigenic El Tor-like hemolysin produced by Vibrio fluvialis

Published in TB and Outbreaks Week, July 29th, 2003

An enterotoxigenic El Tor-like hemolysin produced by Vibrio fluvialis has been purified and characterized.

According to a study from the United States, "The halophilic bacterium Vibrio fluvialis is an enteric pathogen that produces an extracellular hemolysin. This hemolysin was purified to homogeneity by using sequential hydrophobic-interaction chromatography with phenyl-Sepharose CL-4B and gel filtration with Sephacryl S-200."

"It has a molecular weight of 63,000 and an isoelectric point of 4.6, and its hemolytic activity is sensitive to heat, proteases, and pre-incubation with zinc ions," reported Mahendra H. Kothary and colleagues at...

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