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HIV/AIDS Therapy

Novel bean-derived protein has potent antiretroviral and antifungal activity

Published in TB and Outbreaks Week, August 5th, 2003

A novel bean-derived protein has potent antiretroviral and antifungal activity.

According to a study from the Chinese University of Hong Kong, "a protein with an N-terminal sequence displaying similarities to N-terminal sequences of human calcyon and barley endo-1,4-glucanase, and to C-terminal sequences of human translation initiation factor 4gamma and yeast superkiller viralicidic activity, was isolated from the broad bean Vicia faba."

"The protein, termed fabin, has a molecular mass of 34 kDa in SDS-polyacrylamide gel electrophoresis," T.B. Ng and colleagues noted. "Antifungal activity of the protein was observed against several fungal...

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