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TB and Outbreaks Week

Susan Hasty, Publisher

Table of Contents . . . August 12th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in TB and Outbreaks Week | Other Publications

Tuberculosis Diagnosis - Novel PBMC-based tuberculosis immunoassay fast, accurate

Tuberculosis Pathogenesis - Interleukin-8 gene mutations affect tuberculosis susceptibility

Blood Safety - High HTLV-1 rate confirmed in blood donors from Iranian city

Infectious Disease Therapy - Novel acylides active against Gram-positive and -negative pathogens

Legionnaires Disease - Monoclonal antibody typing useful for identifying genotypic subgroups

Pulmonary Tuberculosis Diagnosis - Interferon gamma levels in whole blood can help determine tuberculosis severity

Anthrax - Detrick vaccine tested

Bacterial Pathogenicity - Listerial invasiveness occurs due to listeriolysin O mediated calcium influx

Bacterial Reservoir - Southern chamois in Spain have antibodies to Borrelia burgdorferi

Drug Resistance - Interferometry can be used to determine bacterial drug susceptibility

E. Coli - Cytolethal distending toxin exists in genome or even as a cosmid in many strains

E. Coli - IroBCDEN cluster found on a transmissible plasmid may prove horizontal transfer

E. Coli Pathoadaptivity - Urological virulence appears to be associated with FimH A27V mutation

Genetics and Genomics - Novel E. coli locus useful for pathogenic strain identification

Genomics and Genetics - Unstable GFP variants useful for study of transient mycobacterial gene expression

Helicobacter Pylori - Infection with strains containing cag induces increases in IL-8 receptor

Helicobacter Pylori - Supernatants cause cytoskeletal disruption, not related to VacA toxin

Hygiene - Agreement signed to improve sanitary conditions in indigenous communities

Immunology - Protein that fights bacteria and viruses cloned

Infectious Disease - Exotic animals may carry next outbreak

Infectious Disease - Malaria cases down in Scotland despite increased visits abroad

Infectious Disease - Transmission of Cryptosporidium in cattle tracked in Michigan

Infectious Disease Diagnosis - Novel monoclonal antibodies may aid detection of Norwalk-like viruses

Infectious Disease Epidemiology - Novel enterovirus 71 strain isolated in India

Infectious Disease Therapy - Ceftriaxone superior to penicillin for treatment of severe leptospirosis

Infectious Disease Therapy - Novel chalcones show promise for treatment of leishmaniasis and malaria

Infectious Disease Therapy - Oral ribavirin effective against Crimean-Congo hemorrhagic fever

Influenza - Green algae extract boosts flu vaccine effectiveness in people 50-55

Legionnaires Disease - Pneumonia should be treated with an agent effective against Legionella first

Listeria Monocytogenes - Many low and avirulent strains will likely aid in identifying virulence factors

Malaria Diagnosis - Novel assay enables rapid diagnosis of Plasmodium vivax and P. falciparum malaria

Malaria Pathogenesis - Novel rhoptry-derived protein mediates malaria-infected RBC-endothelial cell adhesion

Malaria Therapy - Heritable RNA interference may be feasible for malaria-carrying Anopheles mosquitos

Malaria Therapy - Novel FR900098 prodrugs show improved antimalarial activity

Malaria Therapy - Novel tetraoxanes active against malaria and some tumors

Public Health - New European agency proposed to tackle future outbreaks, bioterrorist threats

Public Health - Tackling major risk factors simultaneously key to improving global health

Quinolone Resistance - Mechanisms of antibiotic resistance, including resistance gene

SARS - CDC cuts U.S. case count in half

SARS - Interferons explored for treatment

SARS - Singapore eases its anti-SARS measures

Septic Shock - Mortality decreases while frequency increases

Smallpox - Program to vaccinate health workers against smallpox is faltering

Stem Cell Transplantation - Automated assay useful for identifying stem cell recipeints with high CMV disease risk

Tuberculosis Diagnosis - High false positive rate seen with PCR assay

Tuberculosis Diagnosis - LAMP-based assay offers fast, accurate detection of mycobacteria

Tuberculosis Drug Resistance - Novel mycobacteriophage-based assay useful for determining drug susceptibility

Tuberculosis Epidemiology - Genetically distinct "Manila" family of M. tuberculosis identified

Tuberculosis Therapy - Optimal conditions for rifamycin SV production from A. mediterranei determined

Tuberculosis Transmission -  M. tuberculosis infection via laparoscope raises doubts about efficacy of disinfection

Virology - Current infectious diseases threats discussed

West Nile Virus - Clinical trial site intercepts first unit of infected blood

West Nile Virus - Florida blood bank detects West Nile virus in donor

West Nile Virus - Hawaii firm develops vaccine

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