Published in TB and Outbreaks Week, August 26th, 2003
The study found that parasites engineered to lack the molecule known as lipophosphoglycan (LPG) were 10 times more vulnerable to attack by an immune defense known as complement, which is found in the bloodstream. And although parasites that lack LPG easily enter macrophages (immune cells that the parasite normally infects), they were quickly destroyed once inside the cells.
The findings are published online and in the August 5, 2003, issue of the Proceedings of the...
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