Whooping Cough

Genome sequence of Bordetella pertussis revealed

Published in TB and Outbreaks Week, August 26th, 2003

A team of scientists has sequenced the genome of Bordetella pertussis, the highly contagious bacterium that causes whooping cough, which resulted in an estimated 285,000 childhood deaths in 2001, mostly in developing countries.

Writing in the September 2003 issue of Nature Genetics, Julian Parkhill and colleagues also reported the genome sequences of two related bacteria, B. parapertussis and B. bronchiseptica. The comparative analysis of the three genomes helps to clarify the evolution and physiology of these pathogens.

Among the notable findings, Parkhill and colleagues revealed that the three genomes are marked by a...

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Source: TB and Outbreaks Week (2003-08-26)

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