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TB and Outbreaks Week

Susan Hasty, Publisher

Table of Contents . . . September 2nd, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in TB and Outbreaks Week | Other Publications

Infectious Disease - The structure of a key enzyme solved

Pseudomonas Syringae - Leading bacterial pathogen is sequenced

Malaria Diagnosis - Neutrophil lipocalin levels linked to malaria severity

Malaria Pathogenesis -  P. falciparum hastens red blood cell senescence

Malaria Risk Factor - Plasmodial pfcrt K76T mutation unreliable as drug resistance marker

Pulmonary Tuberculosis - Adjunctive interleukin-2 does not improve anti-TB treatment efficacy

Antibacterial Function - Immature dendritic cells have a receptor for human mannan-binding lectin

Antibiotic Research - Resistance may occur in bacteria if innate antibiotic proteins are used

Antibiotic Resistance - Newly discovered inhibitors of bacterial lactamases may prevent resistance

Antibiotic Resistance - World Health Organization: Farmers should cut antibiotic use

Antiviral Therapy - Novel DSTP derivative inhibits growth of HIV and herpesviruses

Blood Safety - All donations now screened for West Nile in U.S.

Citrobacter Braakii - LPS polysaccharide from strain PCM 1531 isn't same as others in group O6

Environmental Health - Aerosolized mycobacteria may underlie respiratory disease outbreaks

Escherichia Coli - The StcE gene was probably acquired by E. coli O157:H7 via plasmid

Finance - Grants to fund rapid, portable detection systems for HIV, blood lead

Food-borne Disease -  Vibrio vulnificus strains vary seasonally in the Galveston Bay estuary

Food-borne Disease - Antimicrobial cocktail may reduce bacteria in fresh-cut produce

Food-borne Disease - Bacteriophage: Poultry's welcome virus

Geriatric Influenza Risk - Influenza A recurrence in myocarditis may cause cardiogenic shock

HIV/AIDS Opportunistic Infection - EGFR is a human cytomegalovirus receptor

HIV/AIDS Opportunistic Infection - Neutralizing antibodies don't prevent gB2 CMV reactivation in HIV patients

HIV/AIDS Opportunistic Infection - Substance P expression linked to diarrhea severity during cryptosporidiosis

HIV/AIDS Tuberculosis - Active case-finding needed to identify HIV patients with TB in Africa

Immune Evasion -  Peptostreptococcus magnus protein L has immunoglobulin binding domains

Infection Control - Company expands Ramoplanin program with launch of infection control study

Infection Susceptibility - Mannose-binding lectin quantity, thus infection resistance, may be genetic

Infectious Disease -  Aeromonas pathogens carry cagA gene from H. pylori

Infectious Disease -  Clostridium species not significant cause of pediatric diarrhea in Brazil

Infectious Disease - Dengue virus serotype 3 viral evolution elucidated

Infectious Disease - Integron-bearing but drug-susceptible E. coli strains found in Rio Grande

Infectious Disease Diagnostics - Dried blood suitable for immunological RNA testing

Infectious Disease Diagnostics - Novel molecular assay improves E. coli detection in beef products

Influenza - Biostatisticians demonstrate method to bolster accuracy of vaccine studies

Influenza - GHRH receptor gene involved in NREMS response to influenza infection in mice

Malaria - Novel activated C kinase receptor helps regulate plasmodial life cycle

Malaria Therapy - Amodiaquine with SP superior to chloroquine for first-line malaria treatment

Meningitis - CIE, LA are best tests for pneumococcal antigen detection

Meningitis - West Nile possible, but not probable, cause of aseptic meningitis

Mergers and Acquisitions - Letter of intent signed for merger with diagnostics company

Monkeypox - Researchers to take blood samples from victims for study

Mosquito-borne Disease -  Aedes albopictus mosquitos do not spread dengue virus

Mosquito-borne Disease - Maize pollen improves Anopheles development

Pathogenic Microorganisms -  Burkholderia cepacia complex and other pseudomonads are phage-infectable

Phagocytosis - Bacterial threat must be gauged during recognition, destruction by macrophages

Plasmodium Falciparum - Study reveals genetic activity of key step in malaria parasite's cycle,

Receptor Signaling - Different adapter proteins help create different microbe-specific TLR signals

SARS - Did rats spread disease in apartment complex?

SARS - Virus will appear again, as will other viruses incubating in "Pandora's boxes"

Sexually Transmitted Diseases - Pregnancy centers initiate program to reduce spread of STDs

Sexually Transmitted Diseases - Report finds low condom use, HIV testing in NYC

Smallpox - Vaccine provides lifelong immunity

Smallpox - Voluntary shots may not protect

Stem Cell Transplantation - GVHD, glucocorticoid treatment impair IPC recovery in stem cell recipients

Stock Market - Infectious disease-focused company approved for AMEX

Toxin Screen - A fluorescent immunoassay can detect enterotoxin B better than ELISA

Tuberculosis Diagnosis - MRI may improve osteoarticular TB diagnosis

Tuberculosis Enzymology - Mycobacterial RecA intein acts as DNA-, Mn2+-dependent ATPase

Tuberculosis Genomics and Genetics - DNA repair gene mutations may improve mycobacterial adaption

Tuberculosis Therapy - Mangosteen-derived agents have potent anti-TB activity

West Nile Virus - Clinical trial cleared for NeuGene against virus; financial results reported

West Nile Virus - Vaccine said to be effective in mice

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