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Plasmodium Falciparum

Study reveals genetic activity of key step in malaria parasite's cycle,

Published in TB and Outbreaks Week, September 2nd, 2003

In a finding that could significantly enhance scientists' ability to develop and test drugs and vaccines to treat the most common and lethal form of malaria, a University of California San Francisco team has identified the full breadth of genetic activity at a key stage of development in the parasite Plasmodium falciparum.

The study, published online in the preview edition of Public Library of Science Biology (PLoS Biology) on August 20, 2003, reveals that an unusually high percentage of genes - at least 60% - were "turned on," or expressed, at the third and critical stage in the parasite's life cycle - when it invades red blood cells and wreaks the...

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