Cerebral Malaria
TNF-alpha, TGF-beta levels have limited prognostic value in children with cerebral malaria
Published in TB and Outbreaks Week, September 16th, 2003
In "a prospective study conducted at the Moi Teaching and Referral Hospital, Eldoret, Kenya," a group of "23 children admitted to the hospital with cerebral (CM) and 10 children with noncerebral malaria (NCM)" were examined "to establish and compare levels of tumor necrosis factor (TNF-alpha) and transforming growth factor (TGF-beta1)".
"Serum and cerebrospinal fluid (CSF) cytokine levels were assayed using ELISA kits. In serum, TGF-beta1 and TNF-alpha decreased over five days after admission to the hospital in both groups of patients...
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