Published in TB and Outbreaks Week, September 23rd, 2003
"A pilot study was carried out on the detection of trypanosome-specific antibodies in saliva for diagnosis of sleeping sickness," scientists in Belgium report.
"All 23 saliva samples of parasitologically confirmed Trypanosoma brucei gambiense patients tested positive in an indirect ELISA, whereas all 14 saliva samples of a negative control group remained negative. Trypanosome-specific antibody levels in patient saliva correlated with antibody levels in serum, but were about 250-fold lower.
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