Tuberculosis Proteomics
Mycobacterial Nudix hydrolase characterized
Published in TB and Outbreaks Week, October 7th, 2003
"Nudix hydrolases are a family of proteins that contain the characteristic sequence GX(5)EX(7)REUXEEXG(I/L/V), the Nudix box," scientists in the United States explained. "They catalyze the hydrolysis of a variety of nucleoside diphosphate derivatives such as ADPribose, Ap(n)A (3 <=n<= 6), NADH, and dATP."
"A number of Nudix hydrolases from several species, ranging from bacteria to humans, have been characterized, including, in some cases, the determination of their three-dimensional structures," noted...
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