TB and Outbreaks Week
Susan Hasty, Publisher
Table of Contents . . . October 14th, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in TB and Outbreaks Week | Other Publications
Drug Development - Mycobacterial arabinogalactan linkage disaccharide analogs block cell wall biosynthesis
Drug Development - Potent inhibitors of M. tuberculosis TMPK developed
Infectious Disease - Rab5 activity, iron access needed for mycobacterial arrest of phagosome maturation
Malaria Therapy - Azadirachta indica derivatives not practical for malaria treatment
Tuberculosis Immunology - TDM needed for macrophage infection with M. tuberculosis
Tuberculosis Latent Infection - M. tuberculosis Rel needed for latent TB infection
AIDS Prevention - Studies to look at role of alcohol in HIV risk in heterosexual women
AIDS Vaccine - HIV vaccine candidate trial begins in 18 cities around the world
Anthrax - Model predicts optimal antibiotic prophylaxis duration during anthrax outbreak
Antibacterial Immunity - Gram-positive bacterial cell walls are identified by innate immune sensors
Antifungal Therapy - Terbinafine safe, effective in children
Antimicrobial Resistance - Burkholderia cepacia is an increasing problem in CF, immunodeficient patients
Catheter-related Infection - Paired DTD values can differentiate catheter and non-catheter bacteremia
Childhood Disease - Babies exposed to Kingella kingae are susceptible to disease after 6 months
Cholera - Dose-ranging study of CholeraGarde confirms immunogenicity
Dendritic Cells - Dendritic cells have defined subsets that are specialized; some fight viruses
Dermatology - Cervicofacial actinomycoses are produced by various genera
Drug Development - Diasteromeric antimalarial agent developed
Drug Development - Jatrorrhizine shows promise as antifungal therapy
Drug Development - Novel plant-derived agents inhibit M. tuberculosis growth
Drug Resistance - Campaign aims to promote awareness of proper antibiotic use
Environment - Health risks from indoor pollution are higher than previously thought
Escherichia Coli - A polymorphism in human IL-8 gene causes E. coli diarrheal symptoms
Finance - Vaccine developer announces board change, provides corporate update
Food Safety - Chicken rinse water can now be tested rapidly for Campylobacter jejuni
Food-borne Illness - Salmonella uses molecular "staples" to change structure of infected cells
Funding - NIH grant to fund Texas center for immunology and biodefense
Funding - Research grant awarded to study natural and bioterrorism salmonella
Gonorrhea - Neutrophil CEACAM3 receptor captures Neisseria gonorrhoeae by two mechanisms
Helicobacter Pylori - H. pylori blocks T cell activation with vacuolating cytotoxin A
Hepatitis B Virus - Import of HBV capsids through nuclear basket observed
Hepatitis B Virus - UNICEF launches emergency vaccination campaign in Peru
Immunology - Human trials begin of investigational HIV prime-boost vaccine candidates
Infection Recognition - Toll-like receptors play a role in both antibacterial and antiviral responses
Infectious Disease - Aldolase gene probe used to identify highly virulent group B streptococci
Infectious Disease - Five-day ciprofloxacin regimen effective against dysentery outbreak in Sierra Leone
Infectious Disease - Viral origin of SARS remains unclear
Influenza - Positive results reported from human challenge study of FluINsure vaccine
Influenza - Vaccinating every child with asthma could prevent 100,000 hospitalizations
Malaria Pathogenesis - Erythrocyte protein target of plasmodial MESA identified
Malaria Therapy - C-2-symmetric inhibitors of Plasmodium falciparum plasmepsin II developed
Malaria Therapy - Cyclosporin-binding P. falciparum proteins identified
Malaria Therapy - Genetic basis of plasmodial drug resistance clarified
Malaria Therapy - Massive funding needed for artesunate-based malaria therapy in Africa
Malaria Therapy - Plasmodial PfCRT expression modulates chloroquine resistance
Malaria Therapy - Plasmodial SAHH structure, function characterized
Opportunistic Infection - Increased antimicrobial use by HIV patients may heighten MRSA risk
Opportunistic Infection - Oral lesions may mark HIV infection in Thai, Cambodian populations
Parasitology - Hormones and drugs that control blood pressure also control malaria
Pregnancy Complications - Macrophage inhibitory cytokine 1 is not an immune regulator in pregnancy
Research Funding - CDC awards $3 million for study of community-associated MRSA
Research Funding - Gates Foundation announces multimillion dollar donation
SARS - Despite new plans, weaknesses remain in U.S. health care
SARS - Health experts confirm Singapore patient was infected in lab
SARS - Positive results reported from study of a new SARS ELISA kit
Streptococcus Pneumoniae - Telithromycin active, in vitro, against multidrug-resistant strains
Syphilis - Epidemic getting much worse in San Francisco
Tuberculosis Diagnosis - FDG PET useful for pulmonary TB detection
Tuberculosis Immunology - Macropinocytosis used in M. tuberculosis internalization by non-phagocytic cells
Tuberculosis Latent Infection - TB toxin blocking phagosome maturation blocks Ca2+/calmodulin-P13K hVPS34 cascade
Tuberculosis Therapy - Genes encoding viomycin biosynthesis from Streptomyces vinaceus identified
West Nile Virus - Researchers study drought as a way to predict disease movement
Whooping Cough - Parents often a source of infection
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