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TB and Outbreaks Week

Susan Hasty, Publisher

Table of Contents . . . October 21st, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in TB and Outbreaks Week | Other Publications

Mosquito-borne Disease - Pototo culture may make bio-pesticide growth cost-effective

Tuberculosis Therapy - PLG microspheres show promise for anti-TB drug delivery

Antibiotics - Linezolid safe for renal damage and hemodialysis patients

Food-borne Disease - Hepatitis A outbreak linked to blueberries in New Zealand

Malaria - Placental Plasmodium falciparum infection alters neonatal immune responses

Scrapie - Brain cytokine gene expression limited in murine scrapie model

Anthrax - Antibodies demonstrate efficacy against anthrax spore challenge

Anthrax - Antidotes to bioterror agent slow to arrive

Antibiotics - Antimicrobials ineffective for NTS eradication

Antibiotics - Azithromycin better tolerated that ABC in ABS patients

Antibiotics - Azithromycin for trachoma control doesn't increase streptococcal resistance

Antibiotics - Novel assay aids detection of antibiotics in water supplies

Antimicrobial Activity - Green tea catechins can act alone or with antibiotics on Helicobacter pylori

Antimicrobial Resistance - Streptococcal tet(O) gene linked to drug resistance

Antimicrobials - Viomycin biosynthesis gene cluster identified in Streptomyces strain

Bacillus Subtilis -  B. subtilis lipoteichoic acid, LPS, endospores can induce IL-6 in macrophages

Childhood Immunization - Have parents behaved irrationally towards MMR?

Drug Development - Lipid agents disrupt mycobacterial actin function

Epidemiology - A sandfly vector survey in Lebanon reveals potential Leishmania transmitters

Escherichia Coli -  E. coli enterohemolysin can be inhibited most by high density lipoprotein

Escherichia Coli - An Escherichia coli strain was found with 4 microcin, MCC V immunity genes

Escherichia Coli - Curliated E. coli generate proinflammatory fibrinopeptides from fibrinogen

Finance - Food safety company reports 21% increase in net income

Funding - Pathologist awarded $1 million grant to study virus assembly

Genomics - Activity of ABthrax described at ICAAC

Genomics - Novel genomic software aids ortholog group identification

Hodgkin Disease - Mononucleosis doubles risk of lymphoma

Immune Evasion - Lyme disease Borrelia species bind factor H, thus cleave C3b complement

Immunology - MBL may opsonize malaria-infected red blood cells

Infectious Disease - 16S rRNA mutations affect H. pylori tetracycline resistance

Infectious Disease - TIGR and NIAID sign $65 million microbial sequencing contract

Infectious Disease Therapy - Rifampin effective against pediatric HGE

Influenza - Nasty Australian flu bug has U.S. officials worried

Leishmaniasis - Phosphoglycan-deficient Leishmania major is a model for persistence studies

Malaria - Insecticidal bed nets introduced in Africa

Malaria - The histone H4 gene is developmentally transcribed in asexual plasmodial parasites

Malaria Animal Models - Olive baboon suitable as malaria infection model

Malaria Genomics - Oligonucleotide array helps clarify P. falciparum genome

Malaria Therapy - Baseline plasmodial atovaquone resistance determined in Africa

Malaria Therapy - Cytochrome P4502C8 and CYP3A4/5 are involved in human chloroquine metabolism

Malaria Therapy - Molecular assay predicts plasmodial drug resistance

Malaria Therapy - Plasmodial pfcrt mutations linked to amodiaquine resistance

Malaria Therapy - Underdosing may hasten malarial drug resistance in Kenya

Medical Error - Group says law would hide patient safety, hospital infection data from public

Melanoma Therapy - Interleukin-12 needed for anti-metastatic effects of Z-100

Meningococcal Disease - New, affordable vaccine stops meningitis

Mosquito-borne Disease - Molecular assay distinguishes An. claviger species

Mosquito-borne Disease - Molecular assay helps distinguish Anopheles species

Mycobacteria - Distinct RecA proteins seen in different mycobacterial strains

Mycobacteria - Key M. tuberculosis enzyme is thermophilic

Mycobacteria - Proteome analysis reveals M. tuberculosis virulence genes

Mycobacterium Smegmatis -  M. smegmatis has an alkaline phosphatase that is a cell surface lipoprotein

Opportunistic Infection - In tropical regions, isosporiasis is common in HIV patients

Oral Biology - Necrotizing stomatitis can be caused by Pseudomonas aeruginosa

Outbreaks - Ciguatera fish poisoning peaks portend cholera outbreaks

Outbreaks - Novel method aids fruit bat urine collection

Personnel - Jerald Sadoff, MD, named CEO of TB vaccine effort

Pneumonia - Pneumococcal vaccine significantly reduces disease in South African children

Pseudomonas Aeruginosa -  P. aeruginosa type 4 O-antigen begins with 2-acetamido-2,6-dideoxy-D-glucose

Public Health - Health officials express concern about flu complacency

SARS - Inadequate plumbing systems likely contributed to disease transmission

SARS - New pact signed to develop vaccine for severe acute respiratory syndrome

SARS - Virus can change quickly and unpredictably, analysis indicates

Smallpox - Project aims to make inoculations safe by "leashing" current vaccine virus

Stem-Cell Transplantation - VZT immunity delayed in cord blood transplant recipients

Tuberculosis Animal Models - SWR mice may be useful for studying TB during immune suppression

Tuberculosis Drug Resistance - Drug-resistant TB highly prevalent in Archangel prison

Tuberculosis Therapy - Discordant mycobacterial kanamycin and amikacin resistance seen

Tuberculosis Therapy - Genomic studies clarify effects of anti-TB drugs

West Nile Virus - CDC says virus will likely spread to California next year

West Nile Virus - Key genomic regions in WNV replication identified

West Nile Virus - West Nile virus causes first death in 2003 in Pennsylvania

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