Published in TB and Outbreaks Week, November 11th, 2003
"The 4-fluoro derivative 2 exhibited markedly enhanced potency and was bioavailable in the rat, dog, and cynomolgus monkey when administered orally as a solution formulation," according to T. Wang and colleagues working at Bristol Myers Squibb Co. in Wallingford, Connecticut. "However, aqueous suspensions of 2 were poorly bioavailable, indicative of dissolution-limited absorption."
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of TB and Outbreaks Week