Drug Development
Novel artemisinin analogues show promise as antimalarial and antileishmanial agents
Published in TB and Outbreaks Week, November 11th, 2003
"Artemisinin (1) and its analogues have been well studied for their antimalarial activity," researchers in the United States noted.
M.A. Avery and colleagues at the University of Mississippi evaluated "the antimalarial activity of some novel C-9-modified artemisinin analogues synthesized using artemisitene as the key intermediate."
In addition, the "antileishmanial activity of more than 70 artemisinin derivatives against Leishmania donovani promastigotes" was "described for the first time," along with the results of a "comprehensive...
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