Atherosclerosis Research
Smooth muscle cells infected with Chlamydia pneumoniae increase MMP-1, MMP-3
Published in TB and Outbreaks Week, December 2nd, 2003
According to recent research published in the journal Fems Immunology and Medical Microbiology, "atherosclerosis has been linked to Chlamydia pneumoniae infection. In atherosclerotic arteries, chlamydiae infect macrophages, endothelial cells, and smooth muscle cells (SMC).
It has been suggested that the proteolysis of the extracellular matrix, by matrix metalloproteinases (MMPs), is involved in the destabilization and rupture of atherosclerotic plaques. In this study, we investigated the expression of several MMPs and tissue...
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