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Biofilms

Antibiotic resistance may be susceptible to genetic approach

Published in TB and Outbreaks Week, December 9th, 2003

Biofilms, slimy clusters of bacteria that are resistant to antibiotics, may have a genetic chink in their armor that could be exploited to combat the infections they cause. A study led by Dartmouth Medical School (DMS) researchers used a genetic-based approach to begin to understand how biofilms can withstand antibacterial treatments.

The results of the study, published in the November 20 issue of Nature, provide an innovative model for the investigation of biofilms that may lead to the development of new methods to hamper their resilience. "We are beginning to get at some of the mechanisms that might be important to understanding the antibiotic resistance of...

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