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Pediatric AIDS

Why do most breastfed infants of HIV-positive moms resist infection?

Published in TB and Outbreaks Week, December 23rd, 2003

Although prolonged breastfeeding is well known to be a major route of transmission of HIV infection to infants and is estimated to cause one-third to one-half of new infant HIV-1 infections worldwide, the majority of breastfed infants with HIV-positive mothers remain uninfected, even after months of exposure.

Investigators at Emory University School of Medicine, the U.S. Centers for Disease Control and Prevention, the Emory Vaccine Center and the University of Paris reviewed the scientific literature to pinpoint the reasons why many breastfed infants resist HIV, with the goal of devising future intervention strategies to prevent newborn infections. Their findings are...

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