Virology

Purdue biologists expose the inner workings of viral machine

Published in TB and Outbreaks Week, January 6th, 2004

Purdue University scientists have peered inside a virus and visualized for the first time how it produces and exports genetic materials into a host cell, an advance in fundamental research that also could have implications for the development of antiviral agents.

Using improved microscope technology, a team including Purdue's Timothy S. Baker and a colleague at Harvard has determined the structure of a reovirus (short for "respiratory enteric orphan" virus) down to the 7.6-angstrom scale, better than twice the 18-angstrom resolution previously available. The newly obtained structure shows not only the molecular composition of the virus but even the position and...

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Source: TB and Outbreaks Week (2004-01-06)

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