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TB and Outbreaks Week

Susan Hasty, Publisher

Table of Contents . . . January 13th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in TB and Outbreaks Week | Other Publications

Antimicrobials - Linezolid does not raise thrombocytopenia risk in nosocomial pneumonia patients

Anthrax - Researchers develop approaches to stop anthrax toxin action

Anthrax - Scientists discover how anthrax creates its deadly spores

Antimicrobial Antibodies - Activated gamma delta T cells go to lymph nodes; increase antibody production

Aphthous Stomatitis - Oral ulceration may indicate Behcet disease, inflammatory bowel syndrome

Blood Transfusion - Blood sterility testing must be from a bag location that avoids false positivity

Childhood Immunization - Invalid vaccine doses would cost millions to fix

Childhood Immunization - Vaccine shortages affect child immunization programs

Combination Therapy - Ethiopia minister blasts doctor's group over treatment

Creutzfeldt Jakob Disease - First case of mad cow found in U.S.

Cryptococcosis -  Cryptococcus neoformans capsule formation can be blocked by RNA interference

Infectious Disease - Action needed to prevent alveolar echinococcosis epidemic in Japan

Drug Development - Burkina Faso medical plants have antimalarial activity

Drug Development - Hematin-targeting 9-anilinoacridines show promise as antimalarials

Drug Development - Modified alpha-GalCer analog has improved antimalarial, anticancer activity

Drug Development - Morning glory extract has antituberculosis activity

Drug Development - Plasmodial aspartic protease characterized

Drug Development - Synthetic cysteine protease inhibitors have potent antimalarial activity

Drug Development - Transformation into gamma-lactone augments quassin's antimalarial activity

Ebola Virus - Solving the Ebola enigma: Satellites will provide clues

Food Technology - Opsonophagocytic assay may be a useful test for safe enterococcal strains

Food-borne Illness - Agency says U.S. outbreaks and deaths from salmonella strain on the decline

Drug Development - 5HTIA serotonin receptor agonists suppress P. falciparum growth

Fungal Infection - CnLYSO1 is an extracellular lysophospholipase of Cryptococcus neoformans

Fungal Infections -  Rhodotorula fungemia isolates respond best to amphotericin B, posaconazole

Fungal Infections - Deep infection by Trichophyton rubrum treatable with itraconazole

Giardia Lamblia - Real-time PCR is at least as effective as antigen assay to detect G. lamblia

HIV/AIDS - Novel trypanosomatids reported in HIV patients

HIV/AIDS Opportunistic Infection -  P. jiroveci DHPS mutations not linked to sulfa drugs in Portugese patients

HIV/AIDS Opportunistic Infection - Alveolar macrophage killing of P. carinii depends on Dectin-1 beta-glucan receptor

HIV/AIDS Tuberculosis - Isoniazid effective against latent TB in HIV+ injection drug users

Helicobacter Pylori -  H. pylori CagA inhibits B cell p53-induced apoptosis; triggers MALT lymphoma

Immunoassay - Optical immunoassay for group B streptococcus works better if infection is heavy

Drug Development - Modified GFP reporter-based assay useful for anti-TB drug screening

Infection Control - CDC releases new guidelines for hygiene in dental care settings

Infection Control - Program designed to help hospitals, physicians slow spread of flu, SARS

Infectious Disease - HIV has significant influence on leishmaniasis epidemiology

Infectious Disease - Schistosomiasis does not affect NTS bacteremia outcome in HIV+ Malawian adults

Influenza - CDC: Flu activity widespread in 45 states

Influenza - Catholic archdiocese asks parishioners with cold or flu to forgo communion

Influenza - Experts: Antiquated flu vaccine system needs updating

Influenza - Flu seems to be hitting kids very hard

Influenza - Health director says "flu shots" sold to Georgia didn't exist

Influenza - Many believed flu shots unnecessary

Drug Development - Plasmodial EBA-140 protein peptides protect blood cells from infection

Influenza - Nursing homes cautious during flu season

Influenza - Plan expands coverage to nasal flu vaccine

Influenza - Race affects older Americans' likelihood of getting flu shot

Influenza - Some turn to homeopathic remedies to combat flu

Influenza - Specialist suggests pregnant women request vaccine to protect both mom and baby

Kala-Azar - Thousands threatened by epidemic in southern Africa

Malaria Diagnostics - PCR assay can aid malaria diagnosis in patients with low parasitemia

Malaria Therapy - Primaquine effective for prevention of malaria in travelers

Malaria Therapy - Two-brood P. falciparum replication during quinine treatment suspected

Measles - Campaign gathers pace on both sides of front line

Tuberculosis Pathogenesis - Mycobacteria-induced SOCS signaling impairs IFN-gamma macrophage stimulation

Mosquito-borne Disease - Delta-class GST from DDT-resistant An. gambiae characterized

Mosquito-borne Disease - Molecular assay aids identification of An. minimus vectors

Neonatal Immunity - Infant immune system finishes developing in the first year of life ex utero

Nosocomial Infection - Antibiotic-resistant bacteria frequently transmitted between ICU patients

Nosocomial Infection - Garlic compound effective against killer MRSA "superbugs"

Periodontal Disease - Subgingival Treponema glycolipids can inhibit TLR, monocyte activation

Personnel - Dr. Lawrence Potempa named chief scientific officer

Polio - U.N.: Spread of polio in West Africa threatens global eradication drive

Regulatory Issues - FDA grants Cipro additional 6 months marketing exclusivity

Rubella - Use of vaccine is growing worldwide, but more work remains

Allergy Medicine - Intranasal RANTES/CCL5 chimera plus truncated exotoxin may prevent fungal asthma

SARS - Hong Kong scientists work on vaccine

Stem-Cell Transplantation - Male gender heightens risk of after hematopoetic SCT late-onset hemorrhagic cystitis

Streptococcus - Opsonophagocytosis assay effective for Streptococcus pneumoniae antibodies

Syphilis - Health departments should adopt new notification policies for gay men

Syphilis - Outbreak in Vancouver said to be world's worst

Tuberculosis Diagnostics - BACTEC MGIT 960 effective for TB drug resistance testing

Tuberculosis Diagnostics - Bronchoscopy with gastric washings provides optimal smear-negative pulmonary TB diagnosis

Anthrax - First FDA-cleared laboratory test for Bacillus anthracis

Tuberculosis Pathogenesis - Microarrays reveal macrophage gene expression after TB infection

Tuberculosis Proteomics - Crystal structure of M. tuberculosis FbpC1 characterized

Tuberculosis Proteomics - Crystal structure of M. tuberculosis MshB protein characterized

Tuberculosis Therapy - Half a million TB patients to get free drugs under new U.N. health agency accord

Typhus - Increase in rodent-transmitted disease seen in Hawaii

Urinary Tract Infection -  Staphylococcus sciuri group may be an infrequent cause of UTI

Varicella-Zoster Virus - Baseline values of herpes zoster among children and adolescents determined

Yersinia Pestis - Humans, rats can be tested for plague using the same, rapid serodiagnostic kit

Anthrax - Judge halts forced military anthrax shots

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