Tuberculosis Pathogenesis
Microarrays reveal macrophage gene expression after TB infection
Published in TB and Outbreaks Week, January 13th, 2004
"High-density oligonucleotide microarrays allow simultaneous monitoring of the expression of a large number of cellular genes," scientists in the United States explained.
In a study conducted by J.P. Wang and colleagues at the University of California-San Diego, "microarrays were used to screen the global human monocyte-derived macrophage transcriptional response to infection with the intracellular pathogen Mycobacterium tuberculosis."
"The microarray detected reproducible patterns of regulated gene expression,"...
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