Infectious Disease

C. parvum-induced intestinal alterations persist after parasite clearance

Published in TB and Outbreaks Week, January 27th, 2004

Intestinal dysfunction associated with cryptosporidiosis persists after the resolution of infection.

"In order to assess the impact of Cryptosporidium parvum on host intestinal physiology," parasitologists in France "investigated absorption of the two principal amino acids in dam's milk (leucine, glutamate), using Ussing chambers and RT-PCR analyses."

"Experiments were performed in both heavily (ileum) and mildly (duodenum) infected segments of the small intestine at the peak of infection [day 8 post-infection (PI)] and after spontaneous clearance of the parasite (day 17 PI)," explained A. Topouchian and coauthors working at Groupe Hospitalier...

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Source: TB and Outbreaks Week (2004-01-27)

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