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Virology

Antibiotics that mimic viruses under development

Published in TB and Outbreaks Week, January 27th, 2004

Scientists have recruited tiny viruses to search for new ways of targeting bacteria with antibiotics. The viruses, termed bacteriophages, give bacteria the equivalent of a nasty cold or worse.

With this in mind, researchers decided to identify the parts of the bacteriophage that do damage to the bacteria. They then exploited this information both to identify the bacterial molecules targeted by the virus and to screen for new antibiotics that inhibit these molecules.

In the February 2004 issue of Nature Biotechnology, Jing Liu and colleagues described their screening system for identifying bacterial targets of phage proteins and show these can...

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