Tuberculosis Immunology
CD40 needed for efficient T-cell priming after M. tuberculosis exposure
Published in TB and Outbreaks Week, February 3rd, 2004
In a study from the United States, "CD40(-/-) mice succumbed to low-dose aerosol infection with M. tuberculosis due to deficient IL-12 production leading to impaired priming of IFN-gamma T-cell responses."
"In contrast, CD40L(-/-) mice were resistant to M. tuberculosis," noted V. Lazarevic and coauthors working at the University of Pittsburgh.
"This asymmetry in outcome of infection between the two knockout strains is likely due to the existence of an alternative...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of TB and Outbreaks Week
More Articles from TB and Outbreaks Week
- SARS
High-dose pulse corticosteroid treatment more effective than low-dose therapy - Collaborations
Alliance to develop, commercialize influenza vaccines - Correctional Health
Treatment in prison can prevent disease outside, says U.S. Surgeon General - Dengue Fever
Thailand epidemics have 3-year cycle - Diphtheria
Federal government report illustrates current diphtheria risks - Drug Development
Glycosylated beta-amino hydroxamates show promise as antimalarials - More from this issue of TB and Outbreaks Week
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
