Tuberculosis Epidemiology
Genetic distance useful as measure of ongoing TB transmission
Published in TB and Outbreaks Week, February 10th, 2004
"The stability of the genotypic marker IS6110, used to define the epidemiology of Mycobacterium tuberculosis, is one of the most important factors influencing the interpretation of DNA fingerprint data," scientists in South Africa explained.
G.D. van der Spuy and colleagues at the University of Stellenbosch proposed that "evolved strains should be considered together with clustered strains to represent chains of ongoing transmission." In their study, the researchers "used a large set of fingerprint data for strains collected between 1992 and 1998 from residents...
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