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Listeria

Lock to food-borne pathogen pathway may be key to vaccine

Published in TB and Outbreaks Week, February 17th, 2004

A previously unidentified protein on the surface of intestinal cells is giving Purdue University researchers clues on how to prevent disease.

The scientists believe their results eventually could lead to a way to prevent food-borne Listeria monocytogenes infection, which has a 20% fatality rate, as well as other diseases. The study of the bacteria is reported in the February 2004 issue of the journal Infection and Immunity.

"This research reveals a detailed mechanism that allows interaction of Listeria with a cell-surface protein, or receptor, on intestinal cells," said Arun Bhunia, a department of food science microbiologist....

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