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Tuberculosis

Genetic risk factors for TB in India reviewed

Published in TB and Outbreaks Week, March 16th, 2004

The genetic risk factors for tuberculosis infection in India have been reviewed.

"Susceptibility to tuberculosis is multifactorial," scientists in India explained. "The importance of host genetic factors on the susceptibility or resistance to tuberculosis has been emphasized by many works.

"Host genetic factors such as human leucocyte antigens (HLA) and non-HLA genes that are associated with the susceptibility to tuberculosis will serve as genetic markers to predispose or predetermine the development of the disease. Such markers may be useful to understand the immune mechanism of susceptibility or resistance to tuberculosis," noted P. Selvaraj and...

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