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TB and Outbreaks Week

Susan Hasty, Publisher

Table of Contents . . . May 11th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in TB and Outbreaks Week | Other Publications

Bioterrorism - Diagnostic algorithm quickly distinguishes anthrax from flu

Drug Development - Aaptamine derivatives show antitumor and antimicroibal activity

Drug Development - Novel endoperoxide antimalarial agents synthesized

Drug Development - Sodium selenite has potent antimalarial activity

HIV/AIDS Therapy - Antiretroviral agents may be useful for SARS prevention and treatment

Anthrax - New type of anthrax vaccine moves into larger-scale trial

Anthrax - Survivors had health problems 1 year after exposure to deadly bacterium

Anti-Infectives - Second-generation triazoles highly effective against opportunistic fungi

Avian Influenza - Officials see little reason for concern over bird flu

Biowarfare - Biodefense applications of recombinant polyclonal antibodies reviewed

Bovine Spongiform Encephalopathy - Mad cow testing issue divides cattle industry

Diagnostics - Monoclonal antibodies useful for FACS detection of intracellular Toxoplasma

Diagnostics - Novel ELISA detects Shiga toxin-producing E. coli in children

Diagnostics - Novel assay improves early detection of ESBL-producing organisms

Diagnostics - Peptide-protein microarrays enable serodetection of multple pathogens

Disease Threat - Tuberculosis case found at Yonkers High School in New York

Drug Development - Novel PNU-100480 analogues have antimycobacterial activity

Drug Development - Peroxyketal function key to activity of G factor-derived antimalarials

Drug Development - Zanamivir derivatives show improved anti-influenza activity

Epidemiology - Impedance method effective for Pseudomonas aeruginosa subtyping

Finance - Biopharma company offers up to 4,000,000 shares of common stock

Gastroenteritis - Asymptomatic people not significant norovirus reservoir

HIV/AIDS Opportunistic Infection - PCR assay detects a variety of fungal pathogens

HIV/AIDS Opportunistic Infection - TMP-SMZ therapy does not select for S. aureus small colony variants

HIV/AIDS Risk - HIV-positive teens not aware of risks and delay treatment

HIV/AIDS Trends - There is hope among grim facts with AIDS

Health Risk - Watermen and scientists warn of "fish handler's disease"

Immunizations - Couple who lost son to whooping cough join immunization push

Immunology -  Entamoeba histolytica L-arginase blocks NO-mediated macrophage activity

Immunology - COLD-FX augments Con-A-induced splenic IL-2 and IFN-gamma production

Immunology - Host immune signals have sex-specific effects on Schistosoma mansoni growth

Infectious Disease - Vertical transmission of Cryptococcus neoformans reported

Influenza - APIC initiative to address low flu-shot rate among healthcare workers

Influenza - Flu shot makers say orders filling up fast for next season

Influenza - Many health care workers not getting flu shot

Influenza - Many healthcare workers not getting flu shot

Lymphoma - Chlamydiae infection may be associated with ocular adnexal lymphoma

Malaria - Transcriptional changes during severe malaria identified

Malaria Drug Resistance -  Plasmodium yoelii mdr1 gene from artemisinin-resistant line characterized

Malaria Drug Resistance - Evolution of drug-resistant P. falciparum in eastern Sudan characterized

Malaria Enzymology - Crystal structure of P. falciparum DHFR-TS determined

Malaria Proteomics - Antigenic cross-reactivity noted between P. falciparum MSP2 alleles

Mosquito-Borne Disease - New season of mosquito-spread illnesses begins

Prion Disease - Variations in infectious protein determine prion strain differences

Public Health - European public health at risk as EU border extends to the east

Rabies Prevention - Pennsylvania begins rabies-baiting program earlier this year

Respiratory Syncytial Virus - Researchers discover cold virus can 'hit and hide'

SARS - China steps up anti-SARS measures

SARS - Interferon-alpha inhibits SARS coronavirus

SARS - Ontario's public health system slammed by interim report on SARS crisis

Salmonella - New faster methods for the detection of food germ developed

Sexual & Reproductive Health - Trichomoniasis found pervasive among high-risk populations

Sexually Transmitted Diseases - Community program helps combat teen STD epidemic

Staphylococcus - Outbreak of skin infections sheds light on risk factors for bacterial resistance

Stem Cell Transplantation - Nonmyeloablative conditioning lowers risk of post-SCT pulmonary complications

Stem Cell Transplantation - Post-SCT antimicrobial treatment practices evaluated

Tuberculosis - Symptoms and treatment of TB-related respiratory failure reviewed

Tuberculosis Diagnostics - PCR TB testing not cost-effective in low-prevalence area

Tuberculosis Drug Resistance - Multiresistance has strong impact on outcome for TB patients in Russia

Tuberculosis Enzymology -  M. tuberculosis thioredoxin reductase characterized

Tuberculosis Enzymology - Crystal structure of M. tuberculosis PKS18 enzyme determined

Tuberculosis Proteomics -  M. tuberculosis Hsp16.3 chaperone activity modulation elucidated

Viral Epidemiology - Andaman and Nicobar Islands tribal school children harbor HBV infections

Viral Vector - Ebola virus glycoproteins guide gene therapies to their destinations

West Nile Virus - Health officials hope West Nile virus cases drop this summer

Wound Care - EGF-induced mitosis increases SLPI levels in keratinocytes

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