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Novel monoclonal antibodies facilitate flow cytometric Toxoplasma detection

Published in TB and Outbreaks Week, June 15th, 2004

Novel monoclonal antibodies facilitate flow cytometric diagnosis of toxoplasmosis.

In a study from South Korea, "[v]arious monoclonal antibodies (mAbs) against Toxoplasma gondii RH tachyzoites were used for flow cytometric detection of intracellular parasites in murine splenic lymphocytes."

"Tg110 and Tg563 (reacting with the major surface protein SAG1), Tg505 (with another surface protein SAG2), Tg695 and Tg786 (with rhoptry proteins), Tg507, Tg621, and Tg317 (with dense granule proteins), Tg536 (with a microneme protein), and Tg685 (with a cytosol antigen) were the mAbs used," explained E.H. Shin and coauthors at Seoul National...

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