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Bacteriology

ProSpecT EIA sensitive and specific for Shiga toxin I and 2 detection in stool

Published in TB and Outbreaks Week, June 29th, 2004

The ProSpecT enzyme immunoassay is sensitive and specific for Shiga toxins I and 2 detection in stool.

According to recent research from the United States, "Shiga toxin-producing Escherichia coli bacteria (STEC) are emerging pathogens capable of producing sporadic and epidemic diarrhea, hemorrhagic colitis, and potentially life-threatening hemolytic-uremic syndrome. Although the presence of E. coli O157 can be readily detected in stool by sorbitol-MacConkey agar culture (SMAC), STEC non-O157 serotypes cannot."

"In contrast to culture," reported P.J. Gavin and coworkers, "testing for the presence of Shiga toxins I and 2 in stool detects...

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