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Anti-Infectives

Terbinafine resolves E. jeanselmei infection in heart transplant recipient

Published in TB and Outbreaks Week, July 20th, 2004

Terbinafine can resolve Exophiala infection in immunosuppressed patients.

According to a case report from Minnesota, an "immunosuppressed heart transplant recipient developed Exophiala jeanselmei infection on the second toe."

"After unsuccessful treatment with different antifungal drugs, the infection responded to a high-dose regimen of oral terbinafine (an antifungal agent not yet approved in the United States for use against the dematiaceous fungi) and warm packs," stated W.A. Agger and coauthors working at the Mayo Clinic in Rochester.

"This is, to our knowledge, the only known case of successful terbinafine...

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